Safety, pharmacokinetics, and food effect of sudapyridine (WX‐081), a novel anti‐tuberculosis candidate in healthy Chinese subjects

• Main Authors: Chengyin Yu (Author), Hongjie Qian (Author), Qingqing Wu (Author), Yang Zou (Author), Qicheng Ding (Author), Yuting Cai (Author), Liyu Liang (Author), Juncai Xu (Author), Lei Li (Author), Bin Zan (Author), Yongguo Li (Author), Yun Liu (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study aimed to assess the safety, pharmacokinetics, and food impact on sudapyridine (WX‐081), a novel drug designed to inhibit mycobacterium ATP synthase, with clinical applications for drug‐resistant tuberculosis (TB) treatment. The research comprised two arms: a single ascending dose...