Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries

• Main Authors: Andre Azevedo Reis Teixeira (Author), Michael Frank Erasmus (Author), Sara D'Angelo (Author), Leslie Naranjo (Author), Fortunato Ferrara (Author), Camila Leal-Lopes (Author), Oliver Durrant (Author), Cecile Galmiche (Author), Aleardo Morelli (Author), Anthony Scott-Tucker (Author), Andrew Raymon Morton Bradbury (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Therapeutic antibodies must have "drug-like" properties. These include high affinity and specificity for the intended target, biological activity, and additional characteristics now known as "developability properties": long-term stability and resistance to aggregation when in so...