Covariate analysis of tusamitamab ravtansine, a DM4 anti‐CEACAM5 antibody‐drug conjugate, based on first‐in‐human study

Abstract Tusamitamab ravtansine is an anti‐CEACAM5 antibody‐drug conjugate indicated in patients with solid tumors. Based on a previous developed semimechanistic model describing simultaneously pharmacokinetic (PK) of SAR408701, two of its active metabolites: DM4 and methyl‐DM4 and naked antibody, w...

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Ngā kaituhi matua: Clemence Pouzin (Author), Michel Tod (Author), Mustapha Chadjaa (Author), Nathalie Fagniez (Author), Laurent Nguyen (Author)
Hōputu: Pukapuka
I whakaputaina: Wiley, 2022-03-01T00:00:00Z.
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