Research on the Species Difference of the Hepatotoxicity of Medicine Based on Transcriptome

• Main Authors: Ziying Xu (Author), Qianjun Kang (Author), Zihui Yu (Author), Lichun Tian (Author), Jingxuan Zhang (Author), Ting Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years, several drugs have been withdrawn from use by regulatory bodies owing to hepatotoxicity; therefore, studies on drug-induced liver injury (DILI) are being actively pursued. Most studies evaluating DILI use rats or mice as animal models to determine drug toxicity; however, the toxicit...