Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model

• Main Authors: Danielle Botelho (Author), Bey F. Leo (Author), Christopher Massa (Author), Srijata Sarkar (Author), Terry Tetley (Author), Kian F. Chung (Author), Shu Chen (Author), Mary P. Ryan (Author), Alexandra Porter (Author), Elena N. Atochina-Vasserman (Author), Junfeng Zhang (Author), Stephan Schwander (Author), Andrew J. Gow (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here we examine the organ level toxicology of both carbon black (CB) and silver nanoparticles (AgNP). We aim to determine metal-specific effects to respiratory function, inflammation and potential interactions with lung lining fluid (LLF). C57Bl6/J male mice were intratracheally instilled with salin...