Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine

• Main Authors: Mohamed S. Pendekal (Author), Pramod K. Tegginamat (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2012-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Tizanidine hydrochloride (THCl) is an antispasmodic agent which undergoes extensive first pass metabolism making it a possible candidate for buccal delivery. The aim of this study was to prepare a monolayered buccal patch containing THCl using the emulsification solvent evaporation method. Fourteen...