Euglycemic Diabetic Ketoacidosis With Prolonged Glucosuria Associated With the Sodium-Glucose Cotransporter-2 Canagliflozin

• Main Authors: Daniel A. Kelmenson MD (Author), Kelsey Burr MD (Author), Yusra Azhar MBBS (Author), Paul Reynolds PharmD, BCPS (Author), Chelsea A. Baker MS, MPAS (Author), Neda Rasouli MD (Author)
• Format: Book
• Published: SAGE Publishing, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sodium-glucose cotransporter-2 (SGLT2) inhibitors improve glycemic control by a reversible inhibition of the sodium-glucose cotransporters in the renal proximal tubules resulting in increased urinary glucose. This unique mechanism, independent of insulin secretion and beta cell function, has made th...