Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats

• Main Authors: Bidemi Emmanuel Ekundayo (Author), Tajudeen Olabisi Obafemi (Author), Blessing Ariyo Afolabi (Author), Olusola Bolaji Adewale (Author), Amos Onasanya (Author), Olukemi Adetutu Osukoya (Author), John Adeolu Falode (Author), Christopher Akintayo (Author), Isaac Adekola Adu (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aim: Gallic acid and metformin are plant-derived compounds with biological effects. The present study aimed to evaluate the protective effect of gallic acid and hesperidin against aluminium chloride (AlCl3)-induced Alzheimer's disease in Wistar rats. Methods: Thirty-five male rats we...