Evinacumab: Mechanism of action, clinical, and translational science

• Váldodahkkit: Robert Dingman (Dahkki), Sébastien Bihorel (Dahkki), Viktoria Gusarova (Dahkki), Jeanne Mendell (Dahkki), Robert Pordy (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2024-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Homozygous familial hypercholesterolemia (HoFH) is a rare and serious genetic condition characterized by premature cardiovascular disease due to severely elevated low‐density lipoprotein cholesterol (LDL‐C). HoFH primarily results from loss‐of‐function (LOF) mutations in the LDL receptor (L...