A New Practice to Monitor the Fabrication Process of Fab-Targeting Ligands from Bevacizumab by LC-MS: Preparation and Analytical Characterization

The objective of this study was to qualitatively evaluate a Fab-targeting ligand preparation containing free thiol groups in the hinge region by using bevacizumab as a model. The evaluation focused on the purification of fragments through a nonaffinity-based process using a centrifugal ultrafiltrati...

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Bibliographic Details
Main Authors: Franck Marquet (Author), Valentina D'Atri (Author), Davy Guillarme (Author), Gerrit Borchard (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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