Ultrasound‐targeted microbubble destruction mediates PDE5i/NO integration for cavernosum remodeling and penile rehabilitation

• Main Authors: Wende Yang (Author), Chen Qiu (Author), Jiancheng Zhai (Author), Wei Zhang (Author), Chengwu Huang (Author), Jun Shao (Author), Jingke Zhang (Author), Shigao Chen (Author), Xiaoyan Miao (Author), Peng Chen (Author), Bo Wei (Author), Jie Ren (Author), Hongbo Wei (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Erectile dysfunction (ED) caused by cavernous nerve injury (CNI) is refractory to heal mainly ascribed to the adverse remodeling of the penis induced by ineffectual microvascular perfusion, fibrosis, and neurotrophins scarcity in cavernosum. Phosphodiesterase type V inhibitors (PDE5i) have...