Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma

• Main Authors: Ana Belen Lopez-Rodriguez (Author), Céline Decouty-Perez (Author), Victor Farré-Alins (Author), Alejandra Palomino-Antolín (Author), Paloma Narros-Fernández (Author), Javier Egea (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the numerous research studies on traumatic brain injury (TBI), many physiopathologic mechanisms remain unknown. TBI is a complex process, in which neuroinflammation and glial cells play an important role in exerting a functional immune and damage-repair response. The activation of the NLRP3...