Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies

• Main Authors: Rocío Piñero-Pérez (Author), Alejandra López-Cabrera (Author), Mónica Álvarez-Córdoba (Author), Paula Cilleros-Holgado (Author), Marta Talaverón-Rey (Author), Alejandra Suárez-Carrillo (Author), Manuel Munuera-Cabeza (Author), David Gómez-Fernández (Author), Diana Reche-López (Author), Ana Romero-González (Author), José Manuel Romero-Domínguez (Author), Rocío M. de Pablos (Author), José A. Sánchez-Alcázar (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nemaline myopathy (NM) is one of the most common forms of congenital myopathy and it is identified by the presence of "nemaline bodies" (rods) in muscle fibers by histopathological examination. The most common forms of NM are caused by mutations in the <i>Actin Alpha 1</i> (<...