Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva.

• Main Authors: Bennett J D Datu (Author), Robin B Gasser (Author), Shivashankar H Nagaraj (Author), Eng K Ong (Author), Peter O'Donoghue (Author), Russell McInnes (Author), Shoba Ranganathan (Author), Alex Loukas (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Third-stage larvae (L3) of the canine hookworm, Ancylostoma caninum, undergo arrested development preceding transmission to a host. Many of the mRNAs up-regulated at this stage are likely to encode proteins that facilitate the transition from a free-living to a parasitic larva. The initi...