Mesenchymal Stromal Cells Cultured in Serum from Heart Failure Patients Are More Resistant to Simulated Chronic and Acute Stress

• Main Authors: Timo Z. Nazari-Shafti (Author), Zhiyi Xu (Author), Andreas Matthäus Bader (Author), Georg Henke (Author), Kristin Klose (Author), Volkmar Falk (Author), Christof Stamm (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite regulatory issues surrounding the use of animal-derived cell culture supplements, most clinical cardiac cell therapy trials using mesenchymal stromal cells (MSCs) still rely on fetal bovine serum (FBS) for cell expansion before transplantation. We sought to investigate the effect of human se...