Metabolic Adaptation-Mediated Cancer Survival and Progression in Oxidative Stress

• Main Authors: Yongquan Tang (Author), Zhe Zhang (Author), Yan Chen (Author), Siyuan Qin (Author), Li Zhou (Author), Wei Gao (Author), Zhisen Shen (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Undue elevation of ROS levels commonly occurs during cancer evolution as a result of various antitumor therapeutics and/or endogenous immune response. Overwhelming ROS levels induced cancer cell death through the dysregulation of ROS-sensitive glycolytic enzymes, leading to the catastrophic depressi...