Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

In this investigation, we extensively studied the mechanism of antitumor activity of bovine pancreatic RNase A. Using confocal microscopy, we show that after RNase A penetration into HeLa and B16 cells, a part of the enzyme remains unbound with the ribonuclease inhibitor (RI), resulting in the decre...

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Main Authors: Islam Saber Ead Mohamed (Author), Aleksandra V. Sen'kova (Author), Oleg V. Markov (Author), Andrey V. Markov (Author), Innokenty A. Savin (Author), Marina A. Zenkova (Author), Nadezhda L. Mironova (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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