Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment

• Main Authors: Zhaoxi Wang (Author), Birgit Claus Henn (Author), Chaolong Wang (Author), Yongyue Wei (Author), Li Su (Author), Ryan Sun (Author), Han Chen (Author), Peter J. Wagner (Author), Quan Lu (Author), Xihong Lin (Author), Robert Wright (Author), David Bellinger (Author), Molly Kile (Author), Maitreyi Mazumdar (Author), Martha Maria Tellez-Rojo (Author), Lourdes Schnaas (Author), David C. Christiani (Author)
• Format: Book
• Published: BMC, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevelopmental outcomes are more frequent and/or more severe when toxic expos...