Transforming growth factor-beta and microRNA-21, microRNA-29b, microRNA-92, and microRNA-129 in systemic sclerosis patients: a case-control study

• Main Authors: Mohammed Hassan Mohammed (Author), Olfat G Shaker (Author), Talal A.Abd El-Raheem (Author), Alaa Abdulkhaleq (Author), Basma H Khatery (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Systemic sclerosis is characterized by extracellular matrix overproduction by activated fibroblasts. It was reported that microRNAs (miRNAs) participate in the regulation of processes that drive fibrosis, which include transforming growth factor-beta (TGF-β) signaling, fibroblast prolifer...