Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression

• Hauptverfasser: Louis Allott (Verfasst von), Cecilia Miranda (Verfasst von), Angela Hayes (Verfasst von), Florence Raynaud (Verfasst von), Christopher Cawthorne (Verfasst von), Graham Smith (Verfasst von)
• Format: Buch
• Veröffentlicht: SpringerOpen, 2019-01-01T00:00:00Z.
• Schlagworte: article
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Abstract Background The histological evaluation of estrogen receptor (ER) and progesterone receptor (PR) expression in breast cancer lesions from biopsy tissue can stratify patients to receive endocrine therapy. Furthermore, PR expression can predict response to selective estrogen receptor modulator...