Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expression

• Main Authors: Louis Allott (Author), Cecilia Miranda (Author), Angela Hayes (Author), Florence Raynaud (Author), Christopher Cawthorne (Author), Graham Smith (Author)
• Formato: Libro
• Publicado: SpringerOpen, 2019-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background The histological evaluation of estrogen receptor (ER) and progesterone receptor (PR) expression in breast cancer lesions from biopsy tissue can stratify patients to receive endocrine therapy. Furthermore, PR expression can predict response to selective estrogen receptor modulator...