DNA Repair Syndromes and Cancer: Insights Into Genetics and Phenotype Patterns
DNA damage response is essential to human physiology. A broad spectrum of pathologies are displayed by individuals carrying monoallelic or biallelic loss-of-function mutations in DNA damage repair genes. DNA repair syndromes with biallelic disturbance of essential DNA damage response pathways manife...
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Frontiers Media S.A.,
2020-10-01T00:00:00Z.
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