Anticancer Drug-Induced Epithelial-Mesenchymal Transition via p53/miR-34a axis in A549/ABCA3 Cells

Anticancer Drug-Induced Epithelial-Mesenchymal Transition via p53/miR-34a axis in A549/ABCA3 Cells

PURPOSE. Several anticancer drugs including bleomycin (BLM) and methotrexate (MTX) cause serious lung diseases such as pulmonary fibrosis. Although evidences showing the association of epithelial-mesenchymal transition (EMT) with pulmonary fibrosis are increasing, the mechanism underlying anticancer...

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Main Authors: Ayano Yamamoto (Author), Masashi Kawami (Author), Takashi Konaka (Author), Shinnosuke Takenaka (Author), Ryoko Yumoto (Author), Mikihisa Takano (Author)
Format: Book
Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
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