Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing

• Main Authors: Jude Madathilethu (Author), Matthew Roberts (Author), Matthew Peak (Author), Joanne Blair (Author), Rebecca Prescott (Author), James L Ford (Author)
• Format: Book
• Published: BMJ Publishing Group, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially unavailable 10 mg tablets, with functional break lines, are split commonly in an attempt to deliver the correct dose. This study aimed to determine the dose var...