Inhibition of Sodium-GlucoseCotransporter 2 with Dapagliflozin in Han: SPRD Rats with Polycystic Kidney Disease

• 主要な著者: Daniel Rodriguez (著者), Sarika Kapoor (著者), Ilka Edenhofer (著者), Stephan Segerer (著者), Meliana Riwanto (著者), Anja Kipar (著者), Ming Yang (著者), Changlin Mei (著者), Rudolf P. Wüthrich (著者)
• フォーマット: 図書
• 出版事項: Karger Publishers, 2015-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background/Aims: Dapagliflozin (DAPA) is a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2) which induces glucosuria and osmotic diuresis. The therapeutic effect of DAPA in progressing stages of polycystic kidney disease (PKD) has not been studied. Methods: We examined the effect of...