Inclusion of a Phytomedicinal Flavonoid in Biocompatible Surface-Modified Chylomicron Mimic Nanovesicles with Improved Oral Bioavailability and Virucidal Activity: Molecular Modeling and Pharmacodynamic Studies

• Hoofdauteurs: Mohamed Y. Zakaria (Auteur), Paris E. Georghiou (Auteur), Joseph H. Banoub (Auteur), Botros Y. Beshay (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Morin hydrate (MH) is a widely-used Asian phytomedicinal flavonoid with a wide range of reported therapeutic activities. However, MH has limited oral bioavailability due to its low aqueous solubility and intestinal permeability, which in turn hinders its potential antiviral activity. The study repor...