Implementation of HLA-B*15:02 Genotyping as Standard-of-Care for Reducing Carbamazepine/Oxcarbazepine Induced Cutaneous Adverse Drug Reactions in Thailand

• Main Authors: Kanyawan Tiwattanon (Author), Shobana John (Author), Napatrupron Koomdee (Author), Pimonpan Jinda (Author), Jiratha Rachanakul (Author), Thawinee Jantararoungtong (Author), Nutthan Nuntharadthanaphong (Author), Chiraphat Kloypan (Author), Mohitosh Biswas (Author), Apisit Boongird (Author), Chonlaphat Sukasem (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study aimed to investigate the clinical impact of HLA-B*15:02 pharmacogenomics (PGx) testing before carbamazepine (CBZ)/oxcarbazepine (OXC) prescriptions and to determine whether this PGx testing was associated with the reduction of CBZ/OXC-induced cutaneous adverse drug reactions (C...