Nobiletin Ameliorates Cellular Damage and Stress Response and Restores Neuronal Identity Altered by Sodium Arsenate Exposure in Human iPSCs-Derived hNPCs

• Egile Nagusiak: Sadaf Jahan (Egilea), Uzair Ahmad Ansari (Egilea), Arif Jamal Siddiqui (Egilea), Danish Iqbal (Egilea), Johra Khan (Egilea), Saeed Banawas (Egilea), Bader Alshehri (Egilea), Mohammed Merae Alshahrani (Egilea), Suliman A. Alsagaby (Egilea), Neeru Singh Redhu (Egilea), Aditya Bhushan Pant (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Environmental exposure to arsenic has been profoundly associated with chronic systemic disorders, such as neurodegeneration, in both experimental models and clinical studies. The neuronal cells of the brain and the nervous system have a limited regeneration capacity, thus making them more vulnerable...