Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice

• Main Authors: Jiale Zhu (Author), Zhiwei Jin (Author), Lei Yang (Author), Caili Zhao (Author), Jianping Hu (Author), Jinhu Chen (Author), Yubao Han (Author), Pei Yu (Author), Jun Luo (Author), Lingyi Kong (Author), Chao Zhang (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Promoting angiogenesis in the ischemic penumbra is a well-established method of ischemic stroke treatment. Ginkgolide B (GB) has long been recognized for its neuroprotective properties following stroke. As previously reported, it appears that stroke-induced neurogenesis and angiogenesis interact or...