Preparation and stability investigation of tamsulosin hydrochloride sustained release pellets containing acrylic resin polymers with two different techniques

• Main Authors: Rui Fan (Author), Yinghua Sun (Author), Bing Li (Author), Ruyi Yang (Author), Wenrui Ma (Author), Jin Sun (Author)
• Formato: Libro
• Publicado: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The objective of this study was to prepare tamsulosin hydrochloride-sustained release (TSH-SR) pellets which showed good release stability with frame-controlled method. TSH was added to Eudragit®NE30D and Eudragit®L30D-55 polymers to form drug-loaded inner core. Afterwards, enteric Eudragit®L30D-55...