Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis

• প্রধান লেখক: Runfang Zhang (লেখক), Tingkui Zhao (লেখক), Beibei Zheng (লেখক), Yun Zhang (লেখক), Xiaohui Li (লেখক), Feng Zhang (লেখক), Juan Cen (লেখক), Shaofeng Duan (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

In this paper, a curcumin derivative Cur20 was synthesized for better hydrolytic stability, which showed a higher angiogenic effect on zebrafish model than curcumin. In order to reveal the potential effects on neuroprotection, a mouse model of vascular dementia (VaD) induced by permanent right commo...