Exposure-response analyses of efzofitimod in patients with pulmonary sarcoidosis

• Main Authors: Gennyne Walker (Author), Ryan Adams (Author), Lauren Guy (Author), Abhijeeth Chandrasekaran (Author), Nelson Kinnersley (Author), Pavithra Ramesh (Author), Lu Zhang (Author), Fran Brown (Author), Vis Niranjan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Preliminary evidence for efficacy in pulmonary sarcoidosis has been shown for efzofitimod. Here we present supportive evidence of efficacy based on an exposure-response analysis.Methods: Data from two studies (Phase 1, N = 24, single dose in healthy volunteers, and Phase 1b/2a, N = 25, m...