4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation

• Main Authors: Ying Gu (Author), Hsi-Ming Lee (Author), Nicole Napolitano (Author), McKenzie Clemens (Author), Yazhou Zhang (Author), Timo Sorsa (Author), Yu Zhang (Author), Francis Johnson (Author), Lorne M. Golub (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2013-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Chronic inflammatory diseases such as periodontitis have been associated with increased risk for various medical conditions including diabetes and cardiovascular disease. Endotoxin (lipopolysaccharide, LPS), derived from gram-negative periodonto-pathogens, can induce the local accumulation of mononu...