KRAS and BRAF mutations in Iranian colorectal cancer patients: A systematic review and meta-analysis

• Auteurs principaux: Abolfazl Yari (Auteur), Asiyeh Afzali (Auteur), Mostafa Aalipour (Auteur), Mehran Nakheai (Auteur), Mohammad Javad Zahedi (Auteur)
• Format: Livre
• Publié: Babol University of Medical Sciences, 2020-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Mutations in the EGFR signaling pathway play an important role in the development of colorectal cancer (CRC). Mutations in these genes, like KRAS and BRAF, affect the treatment strategies and associated with poor prognosis and relative resistance to anti-EGFR therapies. Our aim was to co...