Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics.

• Main Authors: Sacha J Pidot (Author), Jessica L Porter (Author), Laurent Marsollier (Author), Annick Chauty (Author), Florence Migot-Nabias (Author), Cyril Badaut (Author), Angèle Bénard (Author), Marie-Therese Ruf (Author), Torsten Seemann (Author), Paul D R Johnson (Author), John K Davies (Author), Grant A Jenkin (Author), Gerd Pluschke (Author), Timothy P Stinear (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A specific and sensitive serodiagnostic test for Mycobacterium ulcerans infection would greatly assist the diagnosis of Buruli ulcer and would also facilitate seroepidemiological surveys. By comparative genomics, we identified 45 potential M. ulcerans specific proteins, of which we were able to expr...