First description of the katG gene deletion in a Mycobacterium tuberculosis clinical isolate and its impact on the mycobacterial fitness
Isoniazid (INH) is the cornerstone of the anti-tuberculosis regimens and emergence of Mycobacterium tuberculosis (Mtb) resistant strains is a major threat to our ability to control tuberculosis (TB) at global level. Mutations in the gene coding the catalase KatG confer resistance to high level of IN...
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Main Authors: | Flavio De Maio (Author), Antonella Cingolani (Author), Delia Mercedes Bianco (Author), Alessandro Salustri (Author), Ivana Palucci (Author), Maurizio Sanguinetti (Author), Giovanni Delogu (Author), Michela Sali (Author) |
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Format: | Book |
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Elsevier,
2021-05-01T00:00:00Z.
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