A Dual Therapy of Nanostructured Lipid Carrier Loaded with Teriflunomide-A Dihydro-Orotate Dehydrogenase Inhibitor and an miR-155-Antagomir in Cuprizone-Induced C57BL/6J Mouse

• Главные авторы: Trideva Sastri Koduru (Автор), Vishal N. Gupta (Автор), Balamuralidhara Veeranna (Автор), Shanmuganathan Seetharaman (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-04-01T00:00:00Z.
• Предметы: article
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The effective treatment of central nervous system (CNS) disorders such as multiple sclerosis (MS) has been challenging due to the limited ability of therapeutic agents to cross the blood-brain barrier (BBB). In this study, we investigated the potential of nanocarrier systems to deliver miR-155-antag...