Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma

• Main Authors: Moacyr Jesus Barreto de Melo Rêgo (Author), Adriana Azoubel-Antunes (Author), Mariana Brayner-Cavalcanti Freire Bezerra (Author), Michelly Cristiny Pereira (Author), Juliana Cruz da Silva (Author), Thiago Ubiratan Lins e Lins (Author), Emanuel Sávio Cavalcanti Sarinho (Author), Cézar Augusto da Cruz Amorim (Author), Maria do Carmo Alves de Lima (Author), Marina Rocha Galdino-Pitta (Author), Ivan da Rocha Pitta (Author), Maira Galdino da Rocha Pitta (Author)
• Format: Book
• Published: Universidade de São Paulo, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Allergic asthma is a chronic, complex inflammatory disease of the airway. Despite extensive studies on the immunomodulation of T helper (Th) cell pathways (i.e., Th1 and Th2) in asthma, little is known about the effects of Th17 pathway modulation, particularly that involving peroxisome proliferator-...