Filamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy

• Main Authors: Shunshun Han (Author), Can Cui (Author), Xiyu Zhao (Author), Yao Zhang (Author), Yun Zhang (Author), Jing Zhao (Author), Xiaoxu Shen (Author), Haorong He (Author), Jianping Wang (Author), Menggen Ma (Author), Diyan Li (Author), Qing Zhu (Author), Huadong Yin (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FilaminC (Flnc) is a member of the actin binding protein family, which is preferentially expressed in the cardiac and skeletal muscle tissues. Although it is known to interact with proteins associated with myofibrillar myopathy, its unique role in skeletal muscle remains largely unknown. In this stu...