Targeted Co-Delivery of siRNA and Methotrexate for Tumor Therapy via Mixed Micelles

• Main Authors: Fei Hao (Author), Robert J. Lee (Author), Chunmiao Yang (Author), Lihuang Zhong (Author), Yating Sun (Author), Shiyan Dong (Author), Ziyuan Cheng (Author), Lirong Teng (Author), Qingfan Meng (Author), Jiahui Lu (Author), Jing Xie (Author), Lesheng Teng (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A combination of chemotherapeutic drugs and siRNA is emerging as a new modality for cancer therapy. A safe and effective carrier platform is needed for combination drug delivery. Here, a functionalized mixed micelle-based delivery system was developed for targeted co-delivery of methotrexate (MTX) a...