AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice
Objective: Hepatic steatosis is the first step leading to non-alcoholic fatty liver disease, which represents a major complication of obesity. Here, we show that MCT1 haploinsufficient mice resist to hepatic steatosis development when fed a high fat diet. They exhibit a reduced hepatic capacity to m...
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Main Authors: | Lionel Carneiro (Author), Mohamed Asrih (Author), Cendrine Repond (Author), Christine Sempoux (Author), Jean-Christophe Stehle (Author), Corinne Leloup (Author), François R. Jornayvaz (Author), Luc Pellerin (Author) |
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Format: | Book |
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Elsevier,
2017-12-01T00:00:00Z.
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