PPARγ SIGNALING IS REQUIRED FOR MEDIATING EETS PROTECTIVE EFFECTS IN NEONATAL CARDIOMYOCYTES EXPOSED TO LPS

• Main Authors: Victor eSamokhvalov (Author), Jelle eVriend (Author), Kristi L Jamieson (Author), Maria eAkhnokh (Author), Rajkumar eManne (Author), John R Falck (Author), John M. Seubert (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Epoxyeicosatrienoic acids (EETs) are biologically active metabolites of arachidonic acids capable of activating protective cellular pathway...