Augmented Therapeutic Potential of Glutaminase Inhibitor CB839 in Glioblastoma Stem Cells Using Gold Nanoparticle Delivery

Gold nanoparticles (Au NPs) are studied as delivery systems to enhance the effect of the glutaminase1 inhibitor CB839, a promising drug candidate already in clinical trials for tumor treatments. Au NPs were synthesized using a bottom-up approach and covered with polymers able to bind CB839 as a Au-p...

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Autors principals: Beatriz Giesen (Autor), Ann-Christin Nickel (Autor), Juri Barthel (Autor), Ulf Dietrich Kahlert (Autor), Christoph Janiak (Autor)
Format: Llibre
Publicat: MDPI AG, 2021-02-01T00:00:00Z.
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