Characterization of the early inflammatory infiltrate at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites.

• Main Authors: Clarissa Teixeira (Author), Regis Gomes (Author), Fabiano Oliveira (Author), Claudio Meneses (Author), Dana C Gilmore (Author), Dia-Eldin A Elnaiem (Author), Jesus G Valenzuela (Author), Shaden Kamhawi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mice exposed to sand fly saliva are protected against vector-transmitted Leishmania major. Although protection has been related to IFN-γ producing T cells, the early inflammatory response orchestrating this outcome has not been defined.Mice exposed to uninfected P. duboscqi bites and naïve mice wer...