An Overview of the CNS-Pharmacodynamic Profiles of Nonselective and Selective GABA Agonists

• Päätekijät: Xia Chen (Tekijä), Sanne de Haas (Tekijä), Marieke de Kam (Tekijä), Joop van Gerven (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2012-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Various 𝛼2,3 subtype selective partial GABA-A agonists are in development to treat anxiety disorders. These compounds are expected to be anxiolytic with fewer undesirable side effects, compared to nonselective GABA-A agonists like benzodiazepines. Several 𝛼2,3 subtype selective and nonselective GABA...