Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application

• Main Authors: Angela Bonaccorso (Author), Maria Rosa Gigliobianco (Author), Rosalia Pellitteri (Author), Debora Santonocito (Author), Claudia Carbone (Author), Piera Di Martino (Author), Giovanni Puglisi (Author), Teresa Musumeci (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intranasal (IN) drug delivery is recognized to be an innovative strategy to deliver drugs to the Central Nervous System. One of the main limitations of IN dosing is the low volume of drug that can be administered. Accordingly, two requirements are necessary: the drug should be active at a low dosage...