Palmatine protects against atherosclerosis by gut microbiota and phenylalanine metabolism

• Main Authors: Anlu Wang (Author), Baoyi Guan (Author), Linghua Yu (Author), Qiyu Liu (Author), Yuanlong Hou (Author), Ziguang Li (Author), Daming Sun (Author), Hao Xu (Author)
• Format: Book
• Published: Elsevier, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Accumulating evidence illuminated that gut microbiota directly modulates the development of atherosclerosis (AS) through interactions with metaflammation. The natural bioactive isoquinoline alkaloid palmatine (PAL), which is extracted from one of the herbs (Coptis chinensis) of the anti-AS formular,...