Characterization of T-cell immune responses in clinical trials of the candidate RTS,S malaria vaccine

• Asıl Yazarlar: Philippe Moris (Yazar), Erik Jongert (Yazar), Robbert G. van der Most (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The candidate malaria vaccine RTS,S has demonstrated 45.7% efficacy over 18 months against all clinical disease in a phase-III field study of African children. RTS,S targets the circumsporozoite protein (CSP), which is expressed on the Plasmodium sporozoite during the pre-erythrocyte stage of its li...