Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism

• Main Authors: Brittany A. Stork (Author), Adam Dean (Author), Andrea R. Ortiz (Author), Pradip Saha (Author), Nagireddy Putluri (Author), Maricarmen D. Planas-Silva (Author), Iqbal Mahmud (Author), Kimal Rajapakshe (Author), Cristian Coarfa (Author), Stefan Knapp (Author), Philip L. Lorenzi (Author), Bruce E. Kemp (Author), Benjamin E. Turk (Author), John W. Scott (Author), Anthony R. Means (Author), Brian York (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The liver is the primary internal metabolic organ that coordinates whole body energy homeostasis in response to feeding and fasting. Genetic ablation or pharmacological inhibition of calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) has been shown to significantly improve hepa...