Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways

• Główni autorzy: Jing Tang (Autor), Xiaolan Cheng (Autor), Shiyu Yi (Autor), Yuanyuan Zhang (Autor), Zhigang Tang (Autor), Yutong Zhong (Autor), Qiuping Zhang (Autor), Bin Pan (Autor), Yubin Luo (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Toll like receptor (TLR)s have a central role in regulating innate immunity and their activation have been highlighted in the pathogenesis of rheumatoid arthritis (RA). EFL2, one of diterpenoids derived from Euphorbia seeds, is nearly unknown expect for its improving effect on acute lung injury. Our...