Nitric Oxide-Independent cGMP Efflux in the Striatum of Rats Exposed to Carbon Monoxide as Determined by Microdialysis

• Main Authors: Shuichi Hara (Author), Toshiji Mukai (Author), Hajime Mizukami (Author), Fumi Kuriiwa (Author), Takashi Watanabe (Author), Takahiko Endo (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular cGMP in the striatum of rats exposed to 3000 ppm carbon monoxide (CO) or 8% O2 was decreased during the early period of exposure. Thereafter, extracellular cGMP in rats exposed to CO, but not 8% O2, was transiently increased. A nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine,...